International Circulation: Concerning patients with hypertension and diabetes, these conditions are increasing both in Europe and other countries. Now, hypertension patients complicated with impaired glucose tolerance (IGT) are increasing gradually, 1/3 hypertension patients complicated with IGT in Europe, and the percent was 2/3 in China. Are there common pathological mechanisms in both hypertension and diabetes? 《国际循环》:欧洲和其他国家中,高血压合并糖尿病的患者在不断增多。目前,合并糖耐量受损(IGT)的高血压患者也在逐渐增多,在欧洲1/3的高血压患者合并有IGT,在中国这一比例达到2/3。高血压和糖尿病有共同的病理机制吗?
Dr. Yan: In China, the recent epidemiological studies showed that we have 150 million patients with IGT and 92 million with diabetes. This is a very large population of patients with diabetes. Also, in patients with hypertension, the studies show that 62% of hypertensive patients also have a problem with glucose metabolism. This means that it is a very important complication associated with hypertension. We all believe the RAS activation plays an important role in both hypertension and glucose metabolism disorders. In China we advocate using ACE inhibitors or ARBs to treat hypertension complicated with IGT. 严晓伟教授:在中国,近期流行病学研究显示,我们有1.5亿IGT患者和9200万糖尿病患者。这是一个非常庞大的糖尿病患者群体。另外,在高血压患者中,研究显示,62%的高血压患者有糖代谢问题。这意味着它是一个与高血压有关的非常重要的并发症。我们都认为,RAS激活在高血压和糖代谢异常中扮演着重要角色。在中国,我们提倡采用ACE抑制剂或ARBs来治疗合并IGT的高血压。
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